Substance: Testosterone Cypionate
Package: 10 mL vial (250 mg/mL)
Testosterone cypionate belongs to androgens, testosterone dissolved in oil with a cyclopentylpropionate ester (17b-hydroxy-androst-4-en-3-one) attached via 17-beta hydroxyl group, its half-life in the body is approximately 6-8 days (full term work 15-16 days), chemical formula C8H14O2. Cypionate strongly resembles in its action on testosterone enanthate. These forms of testosterone maintain an elevated level of testosterone for 14 days, despite this, talk about a higher water retention with cipionate ether. It is likely that enanthate is slightly better in the issue of testosterone release, due to the fact that this ether is easier for one carbon atom than cypionate (the ether is calculated in the amount of steroids per mg). It should be noted that the difference is so small that it is not even noticeable (it is likely,
In the early 50’s of testosterone, cypionate first appeared on the western market, it was brought out by the company Pharmacia & Upjohn. At first the drug was not widely known, we can say that it was accepted as a substitute for testosterone enanthate in the US market. If you compare these drugs, then they have a small difference – cypionate is not so often a cause of local irritation. Testosterone cypionate is used in clinical settings to treat men with a low level of androgens, which is expressed in a decrease in potency, loss of energy. In the 1960s, the drug was used to improve the structure of bones and for the treatment of menorrhagia and the fight against osteoporosis. In addition, testosterone cypionate for sale was used as a stimulant for spermatogenesis, by 6-10 weeks of suppression of spermatogenesis with doses of 200 mg in 7 days, with the subsequent restoration. By the end of the 1970s, the method of its use was revised, it was no longer used as a remedy for infertility. Testosterone cypionate is one of the most common drugs on the US market, and beyond, including Canada, Australia, Spain, Brazil and South Africa.
Pharmacological action (according to the manufacturer)
Testosterone cypionate has a specific androgenic effect: it stimulates the development and function of the external genitalia, prostate gland, seminal vesicles, including secondary sexual characters in men (voice, hair). He participates in the formation of the constitution of the body and sexual behavior in men, activates libido and potency, stimulates spermatogenesis. Reduces the production of luteotropic and follicle-stimulating hormones. Testosterone is classified as an antagonist of female sex hormones, estrogens. The drug has antitumor effect in breast tumors in women. It has an anabolic effect, it is manifested in stimulating protein synthesis, reducing fat deposition, delaying the body’s necessary potassium, phosphorus, sulfur, calcium fixation in the bones and increasing muscle mass.
Steroid profile of testosterone cypionate
- Activity of the substance: 15-16 days
- Classification: Anabolic / Androgenic steroid
- Method of administration: by injection
- Dosages: Men – 250-1000 mg / week (Women – do not advise)
- Acne: Yes (in large doses or in people with a predisposition)
- Water retention: High
- High blood pressure: Yes (acute conditions are removed with enalapril, but enalapril is not taken on a regular basis, due to the fact that it causes fatigue and apathy)
- Hepatotoxicity: no (testosterone, of course, is in the body of a man, while not affecting the liver, it easily recycles, in this regard, even large doses of any testosterone ester, will not somehow affect the liver)
- Aromatase: high
- DHT (dehydrotestosterone) conversion: yes
- Reduction of HPTA function (development of own testosterone): Yes
- Anabolic activity (100%) \ Androgenic activity (100%)
- The detection time is 4 months (approximately, due to the fact that the DC is constantly progressing in the search for methods for detecting prohibited substances, it also depends on the athlete, whether he takes phenobarbital and furosemide in order to speed up the withdrawal of the drug)
The effects of testosterone testosterone cypionate
- Increased muscle mass
- Strongly improves the strength indicators
- Affects the growth of appetite
- Causes a desire to train
- Reduces pain in the joints
- Affects the strengthening of the osseous system
The use of testosterone cypionate
Admission (for men):
The recommended dosage for athletes is 250-500 (750) mg / week, for a period of 4-12 weeks, these doses are quite enough to achieve high rates, both power and weight typing. Cypionate gives excellent effect in various combinations (Example: Boldenone, Nandrolone) It is not advised to take cypionate in large doses, due to the fact that this does not give a result. The peak concentration of testosterone cypionate after the injection falls on the first three to four days after admission, then gradually the concentration of the drug in the blood decreases. You can say that in order to achieve the concentration of the drug, you need to inject every 4-5th day (or divide the weekly dose into two parts)
Admission (for women):
Women are not advised to take the drug for sport, in connection with high androgenic activity.
Side effects of testosterone cypionate
Excess of estrogen caused by cypionate can lead to the development of gynecomastia, in addition there is a risk of androgenic side effects; increased work of the sebaceous glands, acne, hair growth on the body and face, including male pattern hair loss. (Hereditary, can be circumvented by taking finasteride, but the drug has a side effect – a decrease in libido) in order to minimize the development of side effects advise taking proviron (metacaron), anastrozole or exemestane. After the course of PCT (to restore a high level of endogenous testosterone, without it after the course there is a noticeable decline).
Among the side effects may occur: premature puberty, cancer and prostate anomalies, increased erection and increased sexual arousal, decreased ejaculate volume, oligospermia, premature bone growth closure, depression, headache, anxiety, paresthesia, sleep disturbance, nausea, bleeding in the gastrointestinal tract, cholestatic jaundice, other androgenic effects (including both hirsutism and seborrhea).
Indications for drug use testosterone cypionate
Testosterone replacement therapy in men with pathological conditions associated with primary and secondary hypogonadism, both congenital and acquired, restoration of libido after urogenital operations
Contraindications to the medicinal use of testosterone cypionate
Established or suspected cancer of the prostate or breast, hypersensitivity to any component of the drug, children under 3 years (due to the content of benzyl alcohol), in boys in the pre-pubertal period in order to avoid premature closure of the epiphyses and premature puberty; chronic heart failure, renal and / or liver failure to avoid edema development; diabetes; hypertrophy of the prostate with symptoms of urinary retention; sleep apnea, and risk factors such as obesity and chronic lung disease; childhood.
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